Syria’s official news agency SANA reported that the US airstrike targeted an army checkpoint near Tell al-Zakhab, southeast of the city of Qamishli in Hasakah.
The airstrike reportedly took place after the government checkpoint refused passage to a US patrol that tried to break into a zone controlled by the Syrian Army.
Two helicopters are said to have conducted the attack.
The so-called Syrian Observatory for Human Rights, a London-based monitoring group, claimed that two soldiers were killed in the aerial attack.
In the past, local people in Syrian towns and villages have repeatedly denied passage to US convoys and forced them to return to their illegal bases in areas controlled by Kurdish militants.
The US has been conducting airstrikes and operations against what are said to be Daesh targets inside Syria since September 2014 without any authorization from Damascus or a United Nations mandate.
The US military and its allies in the occupation of Syria have repeatedly been accused of targeting and killing civilians.
The US dispatched new deployments to the Syrian provinces of Hasakah and Dayr al-Zawr following President Donald Trump’s October decision to keep hundreds of US troops in Syria to “secure” the country’s oilfields which Syrian troops have yet to retake from militants.
Syria and its allies in the war on terrorism have said US attempts to control Syria’s oilfields are “illegal” and amount to “robbery.”
The Arab country has been gripped by foreign-backed militancy since March 2011. The Syrian government says the Israeli regime and its Western and regional allies are aiding Takfiri terrorist groups that are wreaking havoc in the country.