Local officials said on Saturday that the attack took place in the Mohammad Agha District of the province late on Friday.
The authorities identified the victims as Taliban militants, who were holed up at a house in the area when the air raid took place.
The Taliban have not yet confirmed any casualties and made no comments on the airstrike.
The US-led forces have increased their airstrikes against civilian areas of Afghanistan in recent months.
At least two people were killed and one more injured on July 6, when US forces launched an airborne assault on the city of Gardez, situated some 100 kilometers (62 miles) south of Kabul.
On July 3, twenty people were killed and nine others injured when foreign forces carried out an airstrike in the Musa Khel district of Afghanistan’s eastern province of Khost.
It came a day after four people were killed in a US-led airstrike in the Miyanishin District of the southern province of Kandahar.
On June 29, eight people were killed when US-led foreign forces launched two separate airstrikes in Paktia and Kandahar provinces.
Also on June 22, at least 30 people lost their lives after US-led forces mounted an airstrike in Afghanistan’s southeastern province of Paktika.
The incident took place at a border checkpoint in the province as Taliban militants were attacking the checkpoint.
Civilian casualties have long been a source of friction between the Afghan government and US-led forces, and have dramatically increased anti-US sentiments in the war-torn country.
The United States and its allies invaded Afghanistan in October 2001 as part of Washington’s so-called war on terror.
The offensive removed the Taliban from power, but insecurity continues to rise across the country, despite the presence of thousands of US-led troops.